Application of Matrix Solid-Phase Dispersion for HPLC analysis of polyphenol profile in 50-years old herbarium specimens of Polygonum aviculare L.
Krzysztof Kapelańczyk¹, Sandra Niezgoda¹, Weronika Kozłowska², Sylwester Ślusarczyk², Anna Prescha³, Adam Matkowski^*2,4
1Student Scientific Association, Department of Pharmaceutical Biology, Wroclaw Medical University
²Department of Pharmaceutical Biology and Botany, Wroclaw Medical University, Wrocław, Poland
³Department of Food Science and Nutrition, Wroclaw Medical University, Wrocław, Poland
⁴Laboratory of Experimental Cultivation of Herbs, Botanical Garden of Medicinal Plants, Wroclaw Medical University, Wrocław, Poland

Phenolic compounds and antioxidant capacity of plum fruits of cv “Čačanska Lepotica” grown on different rootstocks
Viktoria Ivanova^*1, Boryana Trusheva¹, Sava Tabakov², Antoaneta Trendafilova^1
1Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 9, 1113 Sofia, Bulgaria
²Agricultural University, Department of Fruit Growing, Mendeleev Bld., 12, 4000 Plovdiv, Bulgaria

Chemotype Determination of German Chamomile (Matricaria recutita L.) in Ukraine
Ivan Salamon*¹, Maryna Kryvtsova², Miroslava Hrytsyna^3
1Department of Ecology, Faculty of Humanities and Natural Sciences, University of Presov, 01, 17th November St., SK-081 01 Presov, Slovakia
²Department of Genetics, Plant Physiology and Microbiology, Biological Faculty, Uzhhorod National University,  Biological Faculty,  32, Voloshyn St., UA-88000, Uzhhorod, Ukraine
³Department of Pharmacy and Biology, Faculty of Veterinary Hygiene, Ecology and Law, Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, 55, Pekarská St., UA-79040  Lviv, Ukraine

AFLP vs SSR markers in population genetic studies: Genetic diversity of Dalmatian sage (Salvia officinalis L.)
Zlatko Šatović^*1,2, Filip Varga^1,2, Marija Jug-Dujaković³, Martina Grdiša^1,2, Tonka Ninčević³, Klaudija Carović-Stanko^1,2, Zlatko Liber^2,4
1University of Zagreb, Faculty of Agriculture, Svetošimunska cesta 25, 10000 Zagreb
²Centre of Excellence for Biodiversity and Molecular Plant Breeding (CoE CroP-BioDiv), Svetošimunska cesta 25, 10000 Zagreb, Croatia
³Institute for Adriatic Crops and Karst Reclamation, Put Duilova 11, 21000 Split, Croatia
⁴University of Zagreb, Faculty of Science, Marulićev trg 9a, 10000 Zagreb

Composition and content of pyrethrin in different flower development stages of Dalmatian pyrethrum
Filip Varga^*1,2, Martina Biošić³, Dario Dabić³, Zlatko Šatović^1,2, Martina Grdiša^1,2
1University of Zagreb Faculty of Agriculture, Department of Seed Science and Technology, Svetošimunska cesta 25, 10000, Zagreb, Croatia
²Centre of Excellence for Biodiversity and Molecular Plant Breeding, Svetošimunska cesta 25, 10000, Zagreb, Croatia
³Department of Analytical Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia

Biochemical diversity of Immortelle (Helichrysum italicum /Roth./G. Don) populations in Croatia
Tonka Ninčević Runjić*¹, Dejan Pljevljakušić², Martina Grdiša^3,4, Marija Jug-Dujaković¹, Marko Runjić¹, Filip Varga^3,4, Zlatko Šatović^3,4
1Institute for Adriatic Crops and Karst Reclamation, Put Duilova 11, 21000, Split, Croatia
²Institute for the Study of Medicinal Plants „Josif Pančić“, Tadeuša Koščuška 1, Beograd, Serbia
³University of Zagreb, Faculty of Agriculture, Department of Seed Science and Technology, Svetošimunska cesta 25, 10000 Zagreb, Croatia
⁴Centre of Excellence for Biodiversity and Molecular Plant Breeding (CoE CroP-BioDiv), Svetošimunska cesta 25, HR-10000 Zagreb, Croatia

Phytocomponents in treatment of Alzheimer condition
Donika Hoxha^*, Gjoshe Stefkov
Faculty of Pharmacy, Ss. Cyril and Methodius University, Mother Theresa 47, 1000 Skopje, North Macedonia

Richness of Specialized Metabolites in Veronica acinifolia L.  Hydrosols
Marija Nazlić^*1, Dario Kremer ², Karla Akrap¹, Snježana Topić¹, Valerija Dunkić^1
1Faculty of Science, University of Split, Ruđera Boškovića 33, HR-21000 Split, Croatia
²Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10000 Zagreb, Croatia

Antioxidant potential and polyphenol content of five new cultivars of raspberries
Jovana Ljujić^*1, Ivana Sofrenić¹, Iris Đorđević², Predrag Macura¹, Vele Tešević¹, Ljubodrag Vujisić¹, Boban Anđelković^1
1University of Belgrade – Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia
²University of Belgrade – Faculty of Veterinary Medicine, Bulevar oslobođenja 16, 11000 Belgrade, Serbia

Microscopic analysis and the histochemical staining of three species from Asparagaceae family: Hosta plantaginea (Lam.) Asch., Ornithogalum umbellatum L. and Ornithogalum dubium Houtt.
Marin Ștefan-Claudiu^*1, Hovaneț Marilena Viorica², Robert Viorel Ancuceanu², Mihaela Dinu², Cristina Silvia Stoicescu³, Anghel Adriana-Iuliana^2
1”Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Student, 6 Traian Vuia Street, 020956, Bucharest, Romania
²”Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmaceutical Botany and Cellular Biology Department, 6 Traian Vuia Street, 020956, Bucharest, Romania
³“Ilie Murgulescu” Institute of Physical Chemistry, Department of Chemical Thermodynamics, Spl. Independentei 202,P.O.Box. 12-194060021 Bucharest, Romania

Chemical composition, antioxidant and antimicrobial effect of Lavandula essential oil used as a natural antioxidant for cold-pressed oils
Sanja Kostadinović Veličkovska^*1, Dejan Pljevljakušic², Emilija Arsov¹, Saša Mitrev¹, Ljupčo Mihajlov¹, Daniela Dimovska^1
1Faculty of Agriculture, Goce Delčev University, Krste Misirkov bb, 2000 Štip, Republic of North Macedonia
²Institute for Medicinal Plants Research „Dr. Josif Pančić“, Tadeuša Košćuška 1, 11000 Belgrade, Republic of Serbia

Phenolic compound contents and antioxidant activity in different varieties of Hypericum perforatum L. collected from the Republic of North Macedonia
Elizabeta Markoska^*1, Vlado Matevski^1,2, Oliver Tusevski¹, Sonja Gadzovska Simic^1
1Laboratory of Plant Cell and Tissue Culture, Institute of Biology, Faculty of Natural Sciences and Mathematics, University „Ss. Cyril and Methodius“, Arhimedova 3, 1000 Skopje, Republic of North Macedonia
²Macedonian Academy of Sciences and Arts, Krste Misirkov 2, 1000 Skopje, Republic of North Macedonia

Contribution of phenolic acids and flavonols to the antioxidant activity of Hypericum perforatum L.
Ana Zhivkovikj^*, Martina Trajkovska, Oliver Tusevski, Sonja Gadzovska Simic
Laboratory of Plant Cell and Tissue Culture, Institute of Biology, Faculty of Natural Sciences and Mathematics, University „Ss. Cyril and Methodius“, Arhimedova 3, 1000 Skopje, Republic of North Macedonia 

Phytochemical diversity of Rosa canina L. populations in Croatia
Martina Grdiša^*1,2, Jana Šic Žlabur¹, Filip Varga^1,2, Patricija Bosilj¹, Martina Skendrović-Babojelić¹, Tatjana Klepo³, Zlatko Šatović^1,2
1University of Zagreb Faculty of Agriculture, Svetošimunska cesta 25, 10000, Zagreb, Croatia
²Centre of Excellence for Biodiversity and Molecular Plant Breeding, Svetošimunska cesta 25, 10000, Zagreb, Croatia
³Croatian Agency for Agriculture and Food, Center of Pomology, Kralja Zvonimira 14a, 21210 Solin, Croatia

Morphological diversity of natural Dalmatian pyrethrum populations
Kim Klarin¹, Filip Varga^1,2, Ana Nimac², Zlatko Šatović^1,2, Martina Grdiša^*1,2
1University of Zagreb Faculty of Agriculture, Department of Seed Science and Technology, Svetošimunska cesta 25, 10000, Zagreb, Croatia
²Centre of Excellence for Biodiversity and Molecular Plant Breeding, Svetošimunska cesta 25, 10000, Zagreb, Croatia

Effect of peptidomimetics nanofibers, as a carrier of silver on steviol glycoside content of micropropagated Stevia
Maria Geneva¹, Mariana Sichanova¹, Kamelia Miladinova-Georgieva¹, Maria Petrova¹, Elisaveta Kirova¹, Victoria Ivanova¹, Antoaneta Trendafilova^*2
1Institute of Plant Physiology and Genetics, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, Bldg. 21, 1113 Sofia, Bulgaria
²Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, Bldg. 9, 1113 Sofia, Bulgaria

Oxidomics: A new approach to study the lipid oxidation and qualitative properties of cold-pressed vegetable oils
Sanja Kostadinović Veličkovska^*1, Viktorija Maksimova², Saša Mitrev¹, Emilija Arsov^1
1Faculty of Agriculture, Goce Delčev University, Krste Misirkov bb, 2000 Štip, Republic of North Macedonia
²Faculty of Medical Sciences, Goce Delčev University, Krste Misirkov bb, 2000 Štip, Republic of North Macedonia

Total phenolic, total flavonoid and anti-oxidant activity of methanolic extracts of some Centaurea species from Kosovo
Mimozë Buzhala^*, Behxhet Mustafa, Bledar Pulaj, Avni Hajdari
Department of Biology, Faculty of Mathematical and Natural Science, University of Prishtina. Mother Theresa St. 10000 Prishtinë. Kosovo

Chemical composition of the essential oil of hops (Humulus lupulus L.) growing wild in Kosovo
Blerta Salihu*, Bexhet Mustafa, Bledar Pulaj, Avni Hajdari
¹Department of Biology, Faculty of Mathematical and Natural Science, University of Prishtina “Hasan Prishtina”. Mother Theresa St. 10000 Prishtinë. Kosovo

Fractionation and antioxidant properties of Ammi visnaga umbels extracts
Zineb El Jabboury^*1,2, Smail Aazza², Zora Dajić Stevanović³, Stefan Kolašinac³, Ivan Šoštarić³, Meryem Benjelloun¹, Lahsen El Ghadraoui^1
1Laboratory of Functional Ecology and Environmental Engineering, Faculty of Science and Technology, University of Sidi Mohamed Ben Abdellah – Fez, Morocco
²Laboratory of Phytochemistry, National Agency of Medicinal and Aromatic Plants-Taounate, Morocco
³University of Belgrade, Faculty of Agriculture, Nemanjina 6, 11060 Belgrade, Serbia

New insights into sesquiterpene lactones composition of Western Balkan’s genus Amphoricarpos revealed by rapid resolution liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
Milka Jadranin^*1, Mirjana Cvetković¹, Iris Đorđević², Gordana Krstić³, Vele Tešević³, Slobodan Milosavljević^3,4
1University of Belgrade – Institute of Chemistry, Technology, and Metallurgy, Department of Chemistry, Njegoševa 12, 11000 Belgrade, Serbia
²University of Belgrade – Faculty of Veterinary Medicine, Bulevar oslobođenja 18, 11000 Belgrade, Serbia
³University of Belgrade – Faculty of Chemistry, Studentski trg 12–16, 11000 Belgrade, Serbia
⁴Serbian Academy of Sciences and Arts, Kneza Mihaila 35, 11000 Belgrade, Serbia

Essential oil quality of peppermint clones established in cultivation in the village of Bavaniste (South Banat, Serbia)
Ana Stević¹, Ljubiša Kolarić¹, Andreja Komnenić², Dejan Pljevljakušić^*3 
1University of Belgrade, Faculty of Agriculture, Nemanjina 6, 11080 Belgrade, Serbia
²University of Montenegro, Biotechnical Faculty, Cetinjski put 2, 81000 Podgorica, Montenegro
³Institute for Medicinal Plants Research “Dr Josif Pančić”, Tadeuša Košćuška 1, 11000 Belgrade, Serbia

Evaluation of solvent efficiency for extraction of bioactive curcuminoids from turmeric (Curcuma longa L.)
Jana Klopchevska^*1, Aleksandar Chadikovski¹, Zoran Kavrakovski², Marija Srbinoska³, Vesna Rafajlovska^1
1Institute of Organic Technology, Faculty of Technology and Metallurgy, Ss. Cyril and Methodius University in Skopje,  Rudjer Boskovic 16, 1000 Skopje, Republic of North Macedonia
²Institute of Applied Chemistry and  Pharmaceutical Analysis, Faculty of Pharmacy, Mother Theresa 47, Ss. Cyril and Methodius University in Skopje 1000 Skopje, Republic of North Macedonia
³Scientific Tobacco Institute-Prilep, University “St. Kliment Ohridski”-Bitola, Kicevska bb, 7500 Prilep, Republic of North Macedonia

Comparison of mineral content between spontaneous and cultivated flowering stems of Sideritis scardica
Bujar Qazimi^*1, Trajče Stafilov², Katerina Bačeva-Andonovska³, Krsto Tašev⁴, Shpend Dragusha¹, Hyrije Koraqi¹, Vesel Qazimi⁵, Valon Ejupi^1
1Faculty of Pharmacy, UBT- Higher Education Institution, Lagjia Kalabria, 10000 Prishtina, Republic of Kosovo
²Institute of Chemistry, Faculty of Natural Sciences and Mathematics, University Ss. Сyril and Methodius, 1000 Skopje, North Macedonia
³Research Center for Environment and Materials, Macedonian Academy of Sciences and Arts, Bul. Krste Misirkov 2, 1000 Skopje, North Macedonia
⁴State Phytosanitary Laboratory, Bul. Aleksandar Makedonski bb, 1000 Skopje, North Macedonia
⁵Medical High School, “Nikola Shtejn”, Ilinden street. N.n., 1200 Tetovo, North Macedonia

Total polyphenols and flavonoids in Macedonian Oriental tobacco
Marija Srbinoska^*1, Jana Klopchevska², Aleksandar Chadikovski²,  Zoran Kavrakovski³, Vesna Rafajlovska^2
1Scientific Tobacco Institute-Prilep, University “St. Kliment Ohridski”-Bitola, Kicevska bb, 7500 Prilep, Republic of North Macedonia
²Institute of Organic Technology, Faculty of Technology and Metallurgy, Ss. Cyril and Methodius University in Skopje,  Rudjer Boskovic 16, 1000 Skopje, Republic of North Macedonia
³Institute of Applied Chemistry and  Pharmaceutical Analysis, Faculty of Pharmacy, Mother Theresa 47, Ss. Cyril and Methodius University in Skopje 1000 Skopje, Republic of North Macedonia

Chemical composition and antioxidant properties of Juniperus communis L. commercial essential oils from two regions in North Macedonia
Vedrana Bojkovska^*, Marija Karapandzova, Veronika Stoilkovska Gjorgievska, Svetlana Kulevanova, Gjoshe Stefkov, Ivana Cvetkovikj Karanfilova
Institute of Pharmacognosy, Faculty of Pharmacy, “Ss Cyril and Methodius” University in Skopje, Majka Tereza 47, 1000 Skopje, Republic of North Macedonia

Antimicrobial activity of ethyl acetate extract of an endemic Centaurea glaberrima Tausch (Asteraceae)
Milica Miletić^*1, Marija Ivanov², Jelica Novaković¹, Pedja Janaćković^1
1University of Belgrade – Faculty of Biology, Department of Morphology and Systematics of Plants, Studentski trg 16, 11000 Belgrade, Serbia
²Department of Plant Physiology, Institute for Biological Research “Siniša Stanković”, National Institute of Republic of Serbia, University of Belgrade, Bulevar despota Stefana 142, 11000 Belgrade, Serbia

Phenolic profile and antifungal activity of leaf extract of Artemisia absinthium L. (Asteraceae)
Maja Radulović^*1, Milan Gavrilović¹, Uroš Gašić², Nikola Unković¹, Pedja Janaćković^1
1Faculty of Biology, University of Belgrade, Studentski trg 16, 11000, Belgrade, Serbia
²Institute for Biological Research “Siniša Stanković” – National Institute of Republic of Serbia, University of Belgrade, Bulevar despota Stefana 142, 11060, Belgrade, Serbia

Phytochemical screening of the olive variety ‘Istrska Belica’ infected by fungus Venturia oleaginea
Pedja Janaćković^*1, Uroš Gašić², Milan Gavrilović¹, Ivica Dimkić¹, Matjaž Hladnik³, Alenka Baruca Arbeiter³, Dunja Bandelj^3
1University of Belgrade – Faculty of Biology,  Studentski trg 16, 11000 Belgrade, Serbia
²Institute for Biological Research “Siniša Stanković” – National Institute of Republic of Serbia, University of Belgrade, Bulevar despota Stefana 142, 11060, Belgrade, Serbia
³University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies (FAMNIT), Glagoljaška 8, Sl-6000 Koper, Slovenia

Salix alba phytoremediation potential of heavy metals
Demush Bajraktari¹, Lulzim Zeneli², Biljana Bauer^*3
1Faculty of Pharmacy, UBT Higher Education Institution, LagjjaKalabria, p.n. 10000 Prishtine, Kosovo
²Faculty of Education, University “Fehmi Agani”, Str. “Ismail Qemali”, n.n., 50 000, Gjakova, Kosovo
³Faculty of Pharmacy, Ss. Cyril and Methodius, University of Skopje, “Majka Tereza” No. 47, 1000, Skopje, North Macedonia

Raman spectroscopy analysis of rosehip herbal teas
Ilinka Pećinar¹, Stefan Kolašinac^*1, Dragana Rančić¹, Ivan Šoštarić¹, Zora Dajić-Stevanović^1
1University of Belgrade, Faculty of Agriculture, Nemanjina 6, 11080 Belgrade, Republic of Serbia

Conservation of European Biodiversity through Exploitation of Traditional Herbal Knowledge for the Development of Innovative Products.
Konstantia Graikou^*1, Nikolaos Fokialakis¹, Vladimir Dimitrov², Zora Dajic³, Anna Rita Bilia⁴, Jelena Zivkovic⁵, Alberto Dias⁶, Konstantinos Kasiotis⁷, Antreas Afantitis⁸, Konstantinos Gardikis⁹, Mirko Oluški¹⁰, Juan Ramón Muñoz Montaño¹¹, Nektarios Aligiannis^1
1Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Athens, Greece
²Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Acad. Georgi Bonchev 9, 1113, Sofia, Bulgaria.
³Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11080, Belgrade, Serbia.
⁴Department of Chemistry “Ugo Schiff”, University of Florence, Piazza San Marco 4, 50121, Florence, Italy.
⁵Institute for Medicinal Plants Research “Dr Josif Pančić”, Tadeuša Košćuška 1, 171000, Belgrade, Serbia.
⁶Department of Biology and CITAB-UM research Center, University of Minho, Largo do Paço, 4704-553, Braga, Portugal.
⁷Benaki Phytopathological Institute, Stefanou Delta street 8, 14561, Athens, Greece.
⁸Novamechanics Ltd, Prigkipissis Nte Tyras 16 Karantoki Building, 1065, Nicosia, Cyprus.
⁹Apivita SA, Industrial park of Markopoulo, 19003, Athens, Greece.
¹⁰Euro Herbs d.o.o., Lovćenska 7, 21000, Novi Sad, Serbia.
¹¹Zurko Research SL, Calle Gran via 62, 4 Izq, 28013, Madrid, Spain.

Hellenoinos: NMR and LC-MS metabolic profiling of grape skin extracts of six Greek grape varieties
Adamantia-Eleni Manola¹, Antigoni Cheilari*¹, Yorgos Kotseridis², Nektarios Aligiannis^1
1Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Greece
²Department of Oenology, Faculty of Food Science & Human Nutrition, Agricultural University of Athens, 75 Iera Odos, Athens 11855, Greece

Legal approaches for application of cannabis-based preparations in Europe
Emilija Nikolovska^*1, Zorica Naumovska², Zoran Sterjev², Gjoshe Stefkov^2
1Regulatory Affairs Department, Rifam DOO, St.1551 No.10, 1000 Skopje, Republic of North Macedonia
²Ss. Cyril and Methodius University, Majka Tereza 47, 1000 Skopje, Republic of North Macedonia 

Quality requirements for Cannabis flos as final product
Magdalena Hristova^*, Bistra Angelovska
Faculty of medical sciences, University Goce Delcev, Krste Misirkov 10-A, 2000 Stip, N. Macedonia

Individual Approach in Achieving Optimal Balance of THC and CBD in Supplementary Treatment of Neurological Diseases
Gordana Trendovska Serafimovska
HAPA PHARM,  Blvd. “8^mi Septemvri”2-2, 1000, Skopje, N. Macedonia

Basic Recommendations for Creation of Dosage Schedule of Cannabis-based Products based on Benefit / Side Effects Ratio in Supplementary Treatment of Malignant Diseases
Gordana Trendovska Serafimovska^*
HAPA PHARM,  Blvd. “8^mi Septemvri”2-2, 1000, Skopje, N. Macedonia

Comparation of different methods for determination of Cannabis inflorescences humidity
Iskra Davkova^*, Nadica Trajkovska, Ivana Cvetkovikj Karanfilova, Ana Trajkovska, Gjoshe Stefkov, Svetlana Kulevanova, Marija Karapandzova
Ss Cyril and Methodius University in Skopje, Faculty of Pharmacy, Institute of Pharmacognosy, Mother Theresa 47, 1000 Skopje, Republic of North Macedonia

Antimicrobial properties of Cannabis Sativa L. plant
Slavica Dinusheva^*, Aleksandra Pecova
Sinceritas AD Skopje, Anton Panov 11, 1000 Skopje, North Macedonia   

Development and validation of analytical method for microbiological quality control of  Cannabis oil solution: THC 40 mg + CBD 40 mg/1 ml
Marjan Velkovski^*, Damjan Shushleski, Irena Slaveska Spirevska, Elena Metcheva, Silvana Ristevska, Ivana Karchicka
Replek Farm, st. Kozle 188, 1000, Skopje, N. Macedonia

Comprehensive methodology for characterization of Cannabis sativa L. (hemp) inflorescences through combined NMR and LC-based metabolite profiling
Petros S. Tzimas¹, Eleftherios A. Petrakis¹, Stavros Beteinakis¹, Panayiota Papastylianou², Ioanna Kakabouki², Daphne Chandrinou³, Andrea L. Small-Howard⁴, Dimitrios Bilalis², Maria Halabalaki¹, Leandros A. Skaltsounis^*1
1Division of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, 15771 Athens, Greece
²Laboratory of Agronomy, Department of Crop Science, Agricultural University of Athens, 75 Iera Odos Str., 11855 Athens, Greece
³PharmaGnose S.A, Athens, Greece
⁴GbS Global Biopharma, Ottawa, Canada

Post marketing surveillance of cannabis-based preparations
Ivana Josifovska¹, Gjoshe Stefkov², Ivana Cvetkovikj Karanfilova², Aleksandra K. Nestorovska³, Aleksandra Grozdanova³, Zoran Sterjev³, Zorica Naumovska^3
1Varus DOOEL, Faculty of Pharmacy, University “Ss. Cyril and Methodius”, North Macedonia
²Institute of Pharmacognosy, Faculty of Pharmacy, University “Ss. Cyril and Methodius”, Majka Tereza 47, 1000 Skopje, Republic of N. Macedonia
³Institute of Pharmaceutical chemistry, Faculty of Pharmacy, University “Ss. Cyril and Methodius”, Majka Tereza 47, 1000 Skopje, Republic of N. Macedonia

Regulation on pesticide residues use and testing in cannabis and cannabis-based products in North and South America]
Milka Ljoncheva¹, Ivana Cvetkovikj Karanfilova^*2, Gjoshe Stefkov^2
1Jožef Stefan International Postgraduate School, Jamova cesta 39, 1000 Ljubljana, Slovenia
²Institute of Pharmacognosy, Faculty of Pharmacy, University Cc. Cyril and Methodius, Mother Tereza 47, 1000 Skopje, North Macedonia

Analysis of hypoglycemic effects of cannabidiol following oral and intraperitoneal administration in healthy rats
Elona Djemaili^*1, Elena Rafailovska², Aleksandar Dimkovski ³, Evgenija Mihajloska³, Zorica Naumovska³, Gjose Stefkov³, Biljana Miova², Ljubica Suturkova^3
1Department of Pharmacy, Faculty of Medical Sciences, University of Tetova, Ilinden bb, 1200 Tetovo, R.N. Macedonia
²Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University in Skopje, Arhimedova 3, 1000 Skopje, R.N. Macedonia.
³Faculty of Pharmacy, Ss. Cyril and Methodius University in Skopje,  Mother Tereza 47, 1000 Skopje, R.N. Macedonia

Dioscorides’ recipes in two Croatian books of folk recipes
Suzana Inić, Petra Gašparac, Marijana Zovko Končić
University of Zagreb Faculty of Pharmacy and Biochemistry, Ante Kovačića 1, 10000 Zagreb, Croatia

Modulation of adipogenesis by Polygonum hydropiper L. and P. aviculare L. extracts
Martina Savova^*1,2, Apostol Apostolov^1,2,3, Liliya Mihaylova^1,2, Milen Georgiev^1,2
1Department of Plant Cell Biotechnology, Center of Plant Systems Biology and Biotechnology, 4000 Plovdiv, Bulgaria
²Laboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd, 4000 Plovdiv, Bulgaria
³Department of Plant Physiology and Molecular Biology, University of Plovdiv, 24 Tzar Assen, 4000 Plovdiv, Bulgaria 

Orlistat decreases lipid accumulation and affects expression of genes related to lipid metabolism in Caenorhabditis elegans
Apostol Apostolov^1,2,3, Martina Savova^1,2, Monika Todorova^*1,2, Galina Yahubyan³, Milen I. Georgiev^1,2
1Department of Plant Cell Biotechnology, Center of Plant Systems Biology and Biotechnology, 4000 Plovdiv, Bulgaria
²Laboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, Bulgaria
³Department of Plant Physiology and Molecular Biology, University of Plovdiv, 24 Tzar Assen Str., 4000 Plovdiv, Bulgaria 

Discovery of bioactive natural products with skin beneficial properties through the exploitation of ethnobotanical studies conducted in the Balkans
Efthymia Eleni Tsioutsiou^*, Antigoni Cheilari, Nektarios Aligiannis
Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Greece 

PPARγ inhibition mediates Alchemilla monticola Opiz anti-adipogenic effect in human adipocytes
Liliya Mihaylova^*1,2*, Saveta Mladenova³, Martina Savova^1,2, Zhivka Balcheva-Sivenova², Andrey Marchev², Milen I. Georgiev^1,2
1Department of Plant Cell Biotechnology, Center of Plant Systems Biology and Biotechnology, 4000 Plovdiv, Bulgaria
²Laboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd, 4000 Plovdiv, Bulgaria
³BB-NCIPD Ltd., National Center of Infectious and Parasitic Diseases, Ministry of Health, Sofia, Bulgaria

Pharmacovigilance of herbal and traditional herbal medicines
Elena Mladenovska¹, Zorica Naumovska², Zoran Sterjev², Ivana Cvetkovikj Karanfilova³, Aleksandra K. Nestorovska², Gjoshe Stefkov^3
1Euro-farm Skopje, Faculty of Pharmacy, University “Ss. Cyril and Methodius”, North Macedonia
²Institute of Pharmaceutical chemistry, Faculty of Pharmacy, University “Ss. Cyril and Methodius”, Majka Tereza 47, 1000 Skopje, North Macedonia
³Institute of Pharmacognosy, Faculty of Pharmacy, University “Ss. Cyril and Methodius”, Majka Tereza 47, 1000 Skopje, North Macedonia

ANASA – Development of bioactive herbal extracts to treat severe acute respiratory system diseases
Evanthia Dina¹, Dimitrios Toumpanakis², Antigoni Cheilari^*1, Athanasia Chatzianastasiou², Konstantinos Salagiannis³, Sotiris Vasiliadis⁴, Diamanti Ioanna⁵, George Naoum⁶, Andreas Papapetropoulos^3,7, Theodoros Vassilakopoulos^2,8, Nektarios Aligiannis^1
1Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Greece
²“Marianthi Simou” Applied Biomedical Research and Training Center, Evangelismos Hospital Medical School, National and Kapodistrian University of Athens, Greece.
³Clinical, Experimental Surgery and Translational Research Center, Biomedical Research  Foundation of the Academy of Athens, Greece.
⁴Aromafarms LP, Smila, Karoutes, 27065, Ancient Olympia, Greece
⁵Pellas Nature S.A, Seremes, Proastio, 58200, Edessa, Greece
⁶Naumed, 25 Martiou, 42100, Trikala, Greece
⁷Laboratory of Pharmacology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece
⁸Physiology Department, Medical School, National and Kapodistrian University of Athens, Greece

Ex situ conservation and comparative determination of antimicrobial activity of endemic species from genus Stachys
Desislava Mantovska¹*, Detelina Petrova¹, Lyubomira Yocheva², Zhenya Yordanova^1
1Department of Plant Physiology, Faculty of Biology, Sofia University “St. Kliment Ohridski”, Sofia, Bulgaria
²Department of Biology, medicinal genetics and microbiology, Faculty of Medicine, Sofia University, “St. Kliment Ohridski”, Sofia, Bulgaria

Olive oil and olive leaf extracts consumption: A survey on consumer’s attitudes
Jelena Purić¹, Dubravka Bigović^*2, Katarina Šavikin², Jelena Živković², Milan Ilić^1
1Faculty of Pharmacy, University of the Academy of Commerce, Trg mladenaca 5, 21101 Novi Sad, Srbija
²Institute for Medicinal Plants Research “Dr Josif Pančić”, Tadeuša Košćuška 1, 11000 Belgrade, Serbia

Inhibition of glioblastoma growth by Rhodiola rosea L. and its active constituents: An in vitro and in vivo study
Andrey S. Marchev¹, Iliyan K. Manoylov², Gabriela V. Boneva², Silviya L. Bradyanova², Ivanka K. Koycheva¹, Andrey I. Tchorbanov², Milen I. Georgiev^1
1Laboratory of Metabolomics, Department of Biotechnology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd, 4000 Plovdiv, Bulgaria
²Laboratory of Experimental Immunology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev Str., 1113 Sofia, Bulgaria

Traditional use of cultivated plants in Mt. Tara (Western Serbia) – an ethnobotanical survey
Milan Gavrilović^*1, Milica Milutinović¹, Zora Dajić Stevanović², Pedja Janaćković^1
1University of Belgrade, Faculty of Biology, Department of Morphology and Systematics of Plants, Studentski trg 16, 11000 Belgrade, Serbia
²University of Belgrade, Faculty of Agriculture, Department of Agrobotany, Nemanjina 6, 11080 Belgrade, Serbia

In vitro Anti-proliferative Effect of Some Asparagus Taxa on Colon Cancer Cell Lines
Saltan Iscan, G.^*1, Karacaoglu, M.^1,2, Ileri Ozler, H.K.^1,2, Cansaran Duman, D^3
1Ankara University, Faculty of Pharmacy, Department of Pharmacognosy, 06560, Ankara, Turkey
²Ankara University Graduate School of Health Sciences, 06110, Ankara, Turkey
³Ankara University, Biotechnology Institute, 06135, Ankara, Turkey

Identification of anti-epileptic natural products using zebrafish
Alexander D. Crawford^*1,2
1Department of Preclinical Sciences and Pathology, Norwegian University of Life Sciences (NMBU), Elizabeth Stephansens vei 15, 1430 Ås, Norway
²Institute for Orphan Drug Discovery, Bremerhavener Innovations- und Gründerzentrum (BRIG), Stresemannstraße 46, 27570 Bremerhaven, Germany

Traditional approach in prevention and treatment of COVID-19 in Republic of North Macedonia
Biljana Bauer
Faculty of Pharmacy, University of Ss Cyril and Methodius, Mother Theresa 47, 1000 Skopje, Republic of North Macedonia

Traditional knowledge on use of medicinal plants in Central Balkans for treating eczema
Ivan Šoštarić, Sofija Kilibarda, Stefan Kolašinac, Svetlana Aćić, Zora Dajić Stevanović
Universsity of Belgrade, Faculty of Agriculture, Nemanjina 6, 11080 Belgrade, Serbia

Antioxidant potential of Hypericum perforatum L. hairy roots extracts in the kidney of STZ-induced diabetic rats
Elena Rafailovska¹, Cvetanka Trifunovska¹_, Oliver Tushevski², Sonja Gadzovska- Simic², Suzana Dinevska- Kjovkarovska¹_, Biljana Miova^*1
1Department of Physiology and Biochemistry, Institute of Biology, Faculty of Natural Sciences and Mathematics “Ss Cyril and Methodius” University, 100 Skopje, North Macedonia
²Laboratory of Plant Cell and Tissue Culture, Institute of Biology, Faculty of Natural Sciences and Mathematics “Ss Cyril and Methodius” University, 100 Skopje, North Macedonia

Comparative analysis of peel extract and juice obtained from wild and cultivated pomegranate fruits
Milica Radan^*, Zorana Mutavski, Katarina Šavikin, Teodora Janković, Gordana Zdunić, Jelena Živković, Nemanja Krgović, Snežana Kuzmanović-Nedeljković 
Institute for Medicinal Plants Research “Dr Josif Pančić”, Tadeuša Košćuška 1, 11000 Belgrade, Serbia

Use of Hypericum perforatum as food supplement
Angela Ristevski^*1, Riste Ristevski², Elena Jurukovska³, Slavica Jurukovska⁴, Lidija Petrusevska-Tozi^5
1Bayer d.o.o Ljubljana representative office 1000 Skopje, North Macedonia
²Eurofarm doel, 1000 Skopje, North Macedonia
³Ewopharma АG representative office 1000 Skopje, North Macedonia
⁴PHI Health centar1000 Skopje, North Macedonia
⁵Faculty of Pharmacy, “Ss Cyril and Methodius” University in Skopje, Majka Tereza 47, 1000 Skopje, Republic of North Macedonia

Photoprotective properties of myconoside, isolated from Haberlea rhodopensis, under UVA/UVB-induced cytotoxicity in HaCaT cells
Iva Stoykova^*1,2, Ivanka Koycheva^1,2, Biser Binev^1,2, Milen I. Georgiev^1,2
1Center of Plant System Biology and Biotechnology, 4000 Plovdiv, Bulgaria
²Laboratory of Metabolomics, Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd, 4000 Plovdiv, Bulgaria

Modulation of Nrf2 expression in human neutrophils by Ballota nigra extract
Kristiana Amirova^1,2, Petya Dimitrova³, Ivanka Koycheva^*1,2, Jivka Balcheva-Sivenova^1,2, Milen I. Georgiev^1,2
1Department of Plant Cell Biotechnology, Center of Plant Systems Biology and Biotechnology, 4000 Plovdiv, Bulgaria
²Laboratory of Metabolomics, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd, 4000 Plovdiv, Bulgaria
³Department of Immunology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Georgi Bonchev Str., 1113 Sofia, Bulgaria 

Exploitation of ethnopharmacological data towards the discovery of novel wound healing agents
Argyro Vontzalidou^*, Efthymia Eleni Tsioutsiou, Evanthia Dina, Antigoni Cheilari, Nektarios Aligiannis
Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771, Greece

Application of plants from family Caprifoliaceae of the Pirot County (southeastern Serbia) in ethnomedicine
Ksenija Kojičić¹, Vojkan Miljković², Dejan Pljevljakušić³, Biljana Nikolić⁴, Snežana Cupara¹, Ljubinko Rakonjac⁴, Dragoljub Miladinović⁵, Marija Marković^6
1University of Kragujevac, Faculty of Medical Sciences, Department of Pharmacy, Svetozara Markovića 69, 34000 Kragujevac, Republic of Serbia
²University of Niš, Faculty of Technology, Bulevar Oslobođenja 124, 16000 Leskovac
³Institute for Medicinal Plants Research “Dr. Josif Pančić”, Tadeuša Koščuška 1, 11000 Beograd
⁴Institute of Forestry, Beograd, Kneza Višeslava 3, 11030 Beograd
⁵University of Niš, Faculty of Medicine, Department of Pharmacy, Bulevar Dr. Zorana Đinđića 81, 18000 Niš
⁶University of Niš, Faculty of Sciences and Mathematics, Department of Biology and Ecology, Višegradska 33, 18000 Niš

Traditional knowledge of the use of antitumor plants in the Pirot County (Southeastern Serbia)
Ksenija Kojičić¹, Dejan Pljevljakušić², Marija Marković³, Dragoljub Miladinović⁴, Biljana Nikolić⁵, Olivera Papović⁶, Ljubinko Rakonjac⁵, Snežana Cupara^1
1University of Kragujevac, Faculty of Medical Sciences, Department of Pharmacy, Svetozara Markovića 69, 34000 Kragujevac, Republic of Serbia
²Institute for Medicinal Plants Research “Dr. Josif Pančić”, Tadeuša Koščuška 1, 11000 Beograd, Republic of Serbia
³University of Niš, Faculty of Sciences and Mathematics, Department of Biology and Ecology, Višegradska 33, 18000 Niš, Republic of Serbia
⁴University of Niš, Faculty of Medicine, Department of Pharmacy, Bulevar Dr. Zorana Đinđića 81, 18000 Niš, Republic of Serbia
⁵Institute of Forestry, Beograd, Kneza Višeslava 3, 11030 Beograd, Republic of Serbia
⁶University of Priština in Kosovska Mitrovica, Lole Ribara 29, 38220 Kosovska Mitrovica, Republic of Serbia

Soilless propagation of wild Ericaceae medicinal shrubs
Marina Stanilova^*, Boryanka Traykova, Irena Mincheva, Elina Yankova-Tsvetkova
Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, Department of Plant and Fungal Diversity and Resources, 23 Acad. G. Bonchev str., 1113 Sofia, Bulgaria

Evaluation of the antioxidant activity of micropropagated stevia affected by peptidomimetic nanofibers as an Ag carrier
Mariana Sichanova¹, Kamelia Miladinova-Georgieva¹, Maria Petrova¹, Elisaveta Kirova¹, Daniela Tsecova², Maria Geneva^1
1Institute of Plant Physiology and Genetics, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, Bldg. 21, 1113 Sofia, Bulgaria
²Department of Organic Chemistry, University of Chemical Technology and Metallurgy, 8“St. Kl.Ohridski” Blvd, Sofia 1756, Bulgaria  

Flavonoids productivity of wild growing and in vitro cultivated Hypricum species
Antoaneta Trendafilova¹, Viktoriya Ivanova¹, Ina Aneva², Kalina Danova^*1
1Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria
²Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria